Patient Attitudes Towards Self-Administered Epinephrine Devices in Subcutaneous Allergen Immunotherapy

Recent Progress in Allergen Immunotherapy

The efficacy of allergen immunotherapy for the treatment of allergic rhinoconjunctivitis with or without seasonal bronchial asthma and anaphylaxis caused by the sting of the hymenoptera class of insects has been clearly demonstrated in numerous well-designed, placebo-controlled trials. Immunotherapy whether by subcutaneous injection of allergen extract or by oral/sublingual routes modifies peri...

Immunotherapy – 2071. Strail levels decreased after allergen-subcutaneous specific immunotherapy

Background TRAIL is present in cells involved in asthma including eosinophils, mast cells, fibroblasts, and airway epithelial cells. It is expressed in airway remodeling and may be linked with the pathways of transforming growth factorbeta1, which is thought to cause damage to the epithelium. The repair process of the epithelium is hindered as a result of increased apoptosis induced by TGF-beta...

Subcutaneous allergen immunotherapy with dermatophagoides pteronyssinus in patient with local allergic rhinitis

Methods A randomized, double-blind, placebo-controled, parallelgroup, phase II study was conducted. Thirty-six subjects with LAR to DP were randomized to receive Pangraminâ PLUS, ALK, Dermatophagoides pteronyssinus (AIT-DP) or placebo for 24 months. The primary endpoint was total symptoms (TSS) and total medication scores (TMS). Secondary endpoints included: total combined symptom+medication sc...

Efficacy and Safety of Subcutaneous Allergen Immunotherapy for Allergic Rhinitis

Anaphylaxis during specific subcutaneous immunotherapy against ragweed allergen -- case record

Background Recommended by Resolution of Immunotherapy, issued by EAACI, Specific immunotherapy (SIT) was established as a mainstream method of treating allergic diseases. SIT produces long term challenges. SIT team should be aware that at first injection of allergen, the immunotherapy may cause a long lasting reaction. Anaphylaxis during SIT is very rare, but it is possible. We’ve experienced a...